Chorionic villus sampling or placenta puncture

In a chorionic villus sampling, a very small sample of the placenta is taken through the abdominal wall by means of a puncture made under ultrasound guidance. Within 24 hours, deviations in the number of chromosomes, such as trisomy 21, can be excluded using a so-called short-term culture. After two weeks, the so-called long-term culture is available, which also excludes microscopically visible changes in the number of chromosomes. Thanks to technical progress, it is now possible to diagnose even small changes in the genetic material that are not visible on the microscope. Some of these small changes can lead to serious childhood diseases. In connection with a genetic examination, we always recommend a genetic consultation, i.e. a consultation with a doctor of genetics, which we are happy to arrange.

In rare cases, the puncture can trigger contractions, a rupture of the membranes, bleeding or an infection. In 0.1-0.2% of all punctures, this results in a miscarriage.

The chorionic villus sampling is performed during the 12th week of pregnancy at the earliest.